Kidney Disease Stem Cell Therapy in Istanbul, Turkey
How our medical team assesses kidney function, cause and stability, what a plan involves for dialysis patients, and how to send recent labs.
Understanding Chronic Kidney Disease (CKD)
Chronic kidney disease is the gradual loss of the kidneys' filtering capacity, measured as eGFR and staged from mild reduction to kidney failure. Diabetes and high blood pressure cause most of it, with glomerular disease, polycystic kidney disease and long-term inflammation accounting for much of the rest. Symptoms arrive late - fatigue, swelling, poor appetite, disturbed sleep - which is why laboratory numbers do so much of the talking.
Scarring in the kidney, called fibrosis, is what turns injury into permanent loss of function - so that is what treatment is aimed at: the process itself, upstream of the damage it leaves behind. Mesenchymal stromal cells are studied for their influence on immune and inflammatory activity and for signals that interact with the pathways driving fibrosis. Our cells are grown from Wharton's jelly, the gelatinous tissue inside a donated umbilical cord, and because that source expands readily in culture, a batch is characterised and release-tested before it is given to anyone. Nephrons already lost do not come back, and our team is direct about that rather than leaving it implied.
Our medical team reviews the cause of your kidney disease, the trend in eGFR and creatinine over recent years rather than a single value, urine protein, electrolytes including potassium, blood pressure control, fluid status, anaemia and bone mineral results, and your full medication list. For dialysis patients it also plans around the schedule and protects the access site. Where treatment is appropriate, the aim may focus on energy, appetite and daily wellbeing, with nephrology care and transplant assessment continuing. Send several years of kidney results rather than a single set, so our medical team can read the trend.
How Chronic Kidney Disease (CKD) Can Affect Daily Life
Symptoms, severity and progression vary from person to person. Our medical team uses this kind of detail as context for your case review; it is not a diagnostic checklist. Diagnosis, and any change in your symptoms, belong with the clinician who knows your medical history.
- Fatigue
- Swelling in legs or feet
- Changes in urination
- Reduced appetite
- Weakness or reduced tolerance for daily activity
Kidney health is measured as a trend
Chronic kidney disease affects filtration, fluid, electrolytes, blood pressure, blood production, and bone health. The visual keeps cause, stage, and direction of travel together.

Clinical context

Microscopic research viewIllustrative detail
- Filtration units
- Nephrons filter blood and help regulate fluid, electrolytes, acid balance, and waste removal.
- Cause and trajectory
- Estimated filtration rate, urine protein, blood pressure, diabetes control, imaging, and medication mean most as a trend.
- Advanced-care context
- Anemia, mineral balance, swelling, cardiac risk, dialysis, and transplant planning can take clinical priority.
Why Regenerative Medicine Is Being Studied in CKD
These are the biological mechanisms researchers are investigating. A mechanism is a reason to study a treatment, not a promise of benefit for an individual patient. Our medical team will explain how much of this research applies to your own diagnosis.
- MSCs are studied for their influence on immune and inflammatory activity, known as immunomodulation
- In the kidney the research also examines signals that interact with the pathways driving scarring, called fibrosis
- Nephrons already lost are not replaced, and our team states that rather than implying otherwise
- Infusion volume and electrolytes are planned around your fluid status and kidney function
- Dialysis scheduling, access protection and transplant assessment continue on their own timetable
- The aim may focus on energy, appetite and daily wellbeing, reviewed with your nephrologist
Research maturity
What the Research Currently Shows for CKD
How far published research has travelled for each approach, from laboratory work through to established standard care. It describes the maturity of the evidence, not how well any option works and not what to expect in an individual case.
- 01Laboratory and animal work
- 02Early human studies
- 03Controlled trials under way
- 04Established standard of care
RAAS blockade, SGLT-two inhibition, blood pressure control and renal replacement
Standard nephrological care with large outcome trials showing slower eGFR decline and reduced cardiovascular risk.
Established standard of care
Mesenchymal stromal cell infusion in diabetic or inflammatory kidney disease
Early-phase human trials examine safety and microvascular inflammation; no cell therapy replaces dialysis or transplantation in advanced renal failure.
Early human studies
The proposed mechanism, illustrated
What is being studied in the tissue in CKD
Your case review
How Our Medical Team Reviews Your Case
Your review starts with the confirmed diagnosis, recent reports and imaging, current treatment, medical history, and the outcome that matters most to you. Not everyone is suitable for regenerative medicine, and our team will say so when the care you already receive is the better route.
- A confirmed CKD diagnosis with the underlying cause documented
- Recent creatinine, eGFR, electrolytes and urine protein, ideally with results from previous years
- Blood pressure readings and current antihypertensive medication for our team to review
- Dialysis schedule and access details where dialysis has started
- Transplant assessment status, which continues regardless of any plan we propose
- Medical stability for travel, reconfirmed close to the date rather than only at review
How Treatment for CKD Is Planned at Our Istanbul Clinic
The path international patients follow with us, from the first review of your records to follow-up after you return home. The exact steps depend on what your medical review finds.
Send your medical records
Recent reports, imaging, your current medication, and what you hope treatment will help with. It lets our medical team make the review specific to you.
Start your case reviewSend your medical records
Your case review starts with the confirmed diagnosis, recent reports and imaging, current medications, previous procedures and the outcomes that matter most to you. Everything can be sent digitally from home, long before travel is discussed.
Case review by our medical team
Our medical team reads the file against your diagnosis, disease stage, imaging, laboratory results, current treatment and any contraindications, then decides whether regenerative medicine is appropriate for you and which goals are realistic to discuss.
Your written treatment plan
When treatment is appropriate, you receive the plan in writing: the cell material and how it is prepared, the dose, the route of administration, the number of sessions, the monitoring involved and an itemized cost with no assumed extras.
Your treatment in Istanbul
On arrival our team repeats the checks that matter for your case, confirms the plan with you, and carries out treatment under medical supervision with an observation period afterwards. Your coordinator handles scheduling, timings and what each day involves.
Follow-up and monitoring
Before you fly home we agree what will be measured, when it will be reviewed and how to reach us. Follow-up continues remotely and can be shared with your own doctors, so your treatment plan and your local care stay aligned.
Your treatment plan
What Our Medical Team Explains Before You Decide
"Stem cells" and "exosomes" name a category, not a specific product. What matters in your plan is the source of the material, how it was prepared, the route and the dose, the clinical setting, and why you were considered suitable. Our medical team sets each of those out for the treatment being proposed to you.
We plan treatment alongside the care you already receive, so keep your own clinician involved and record a clear baseline before you travel. For the practical side, read the Istanbul treatment trip guide and the cost guide, then ask us for an itemized estimate.
- Which published research applies to your diagnosis and to the route we propose.
- Where the biological material comes from, how it is prepared, and how it is documented.
- The possible side effects and the contraindications that apply to your procedure.
- Which functional outcome is measured before treatment and again at follow-up.
- How treatment sits alongside your existing care, including the option of not treating.
- Who to contact about follow-up, or about a complication, once you are home.
- What your estimate includes and excludes, and what is due before you travel.
Next step
Start with a medical case review
Send your diagnosis, recent reports, imaging and current medication, and tell us what you want treatment to help with.
Chronic Kidney Disease (CKD): Questions Patients Ask Us
What does kidney disease stem cell therapy cost in Istanbul, Turkey?
Kidney function monitoring, adjustments to infusion volume and, for dialysis patients, sessions arranged locally during the stay all add to the treatment cost. Our patient coordination team quotes dialysis and transport explicitly rather than assuming them, and prices the follow-up plan too.
Can dialysis patients be treated in Istanbul?
They can be assessed, and the logistics are planned in detail: dialysis sessions arranged around treatment days, fluid balance managed between them, the access site protected, and medication timing coordinated with your home unit. Our team liaises with that unit before you travel.
Will treatment affect my place on a transplant list?
Transplant assessment is the priority and our team will not suggest postponing it. We ask where you stand in that process, share the written plan with your nephrologist, and decline treatment where it could complicate the pathway you are already on.
Are Wharton's jelly stem cells used to treat Chronic Kidney Disease (CKD) in Istanbul?
Yes. Our regenerative medicine program works with mesenchymal stromal cells (MSCs) grown from Wharton's jelly, the gelatinous tissue inside the umbilical cord. It is donated after a healthy birth with written maternal consent, from tissue that would otherwise be discarded, so nothing is taken from mother or baby and none of the ethical questions attached to embryonic sources arise. Because these cells expand readily in culture, a batch is characterised and release-tested before it reaches anyone. Your written plan names the material, how it is prepared, the dose, the route of administration and the schedule, and our medical team explains why each of those was chosen for your case.
Why use donor cells from Wharton's jelly rather than my own cells for Chronic Kidney Disease (CKD)?
Wharton's jelly is a young, perinatal tissue rather than an adult one, so the starting material does not carry the age or the health history of the person being treated, and nothing has to be harvested from you on the day. These cells also have a low-immunogenicity profile, which is why this source is studied for use between unrelated people. Most of all, they are strong secretors: the signalling molecules MSCs release are the mechanism most current research centres on, and that is what a plan is built around.
How long do international patients stay in Istanbul for Chronic Kidney Disease (CKD) treatment?
The length of stay follows your plan: the route of administration, the number of sessions, the monitoring after each one, and any mobility or assistance you need. Our patient coordination team confirms appointment dates, daily timings and the expected length of the visit in writing before you book flights.
Is stem cell therapy for Chronic Kidney Disease (CKD) safe?
No medical procedure is free of risk. Our medical team screens for infection, bleeding risk, medication interactions and other contraindications before treatment, explains the risks specific to the route used in your plan, and monitors you during administration and afterwards. If something makes treatment unsafe for you, we say so instead of proceeding.
What can stem cell therapy realistically aim for in Chronic Kidney Disease (CKD)?
Goals are set with you and described as aims, not results. Regenerative medicine treatments are planned individually, responses vary between patients and no clinical outcome can be guaranteed. Your plan states what will be measured, when it will be reviewed, and how treatment sits alongside the care you already receive.
How do I start a Chronic Kidney Disease (CKD) case review from outside Turkey?
Send your confirmed diagnosis, recent reports and imaging, your current medication list, previous procedures and the goals that matter to you. Our medical team reviews them remotely and comes back with an assessment of whether treatment in Istanbul is appropriate for your case, and what the next step would be.
Medical Disclaimer: Information on this page is educational and is not personal medical advice. Regenerative medicine treatments are planned individually, responses vary and no clinical outcome can be guaranteed. Some of the approaches described remain investigational. Suitability is confirmed only after medical review, and treatment is planned alongside your existing care.

Sunrise from Istanbul's Asian shore, looking across the water. It shows the city you would travel to, not our clinic, your accommodation, or a service included in a plan.
Keep renal care continuous while you travel
For CKD, our team coordinates recent laboratory records, medication, fluid guidance, dialysis where relevant, and follow-up before Istanbul travel is booked.
Keep researching
Treatments and Related Conditions for Chronic Kidney Disease (CKD)
Treatment
Intravenous Stem Cell Therapy
How an infusion session runs, how you are monitored, and when our team proposes this route.
Learn more→
Treatment
Umbilical Cord MSC Therapy
The cord-tissue mesenchymal cells we work with, from donor screening to batch release testing.
Learn more→
Condition
Diabetes
How regenerative medicine is planned for Diabetes at our Istanbul clinic.
Learn more→
Condition
Heart Disease (Heart Failure)
How regenerative medicine is planned for Heart Disease (Heart Failure) at our Istanbul clinic.
Learn more→
Condition
Liver Failure
How regenerative medicine is planned for Liver Failure at our Istanbul clinic.
Learn more→
Condition
Chronic Obstructive Pulmonary Disease (COPD)
How regenerative medicine is planned for Chronic Obstructive Pulmonary Disease (COPD) at our Istanbul clinic.
Learn more→
More from our clinic
Planning treatment for CKD in Istanbul
The practical side of treatment at our clinic: what the research shows, who may be suitable, what a plan costs, and how your stay in Istanbul and your follow-up are arranged.
Cost, Outcomes & Istanbul
- Visit our Istanbul clinicWhere we are, how patients reach us, and what to arrange before you travel.
- Understand treatment pricingWhat shapes a quote, and what an itemized estimate from our clinic covers.
- Planning your Istanbul treatment tripRecords, travel timing, local transport, accommodation, and follow-up after you fly home.
- Choosing a stem cell clinic in IstanbulHow we document candidacy, pricing, clinical oversight, and aftercare for international patients.
- Rules and oversight in TurkeyHow regenerative medicine is regulated in Türkiye, and the paperwork that accompanies treatment.
- Reading stem cell success ratesWhat a published percentage can and cannot tell you about your own diagnosis.
- What your treatment quote includesWhat the clinical fee covers, which items are listed separately, and what moves the total.
- What to expect during treatmentThe remote case review, your written plan, the treatment day, and follow-up once you are home.
- Longevity and healthy-ageing care in IstanbulWhat our longevity programme assesses, and how it differs from treating a diagnosed condition.
- What exosome treatment in Istanbul costsHow we structure an exosome quote, and the line items a written estimate names.
- Exosome therapy questions we are askedSourcing, dosing, regulation, and the documentation that accompanies a proposed treatment.
- Medical travel to Turkey: patient guideHow remote record reviews, clinic scheduling, and travel logistics fit together.
- Comparing treatment abroad: Turkey vs MexicoQuestions to ask when comparing clinics, cell documentation, and oversight across countries.
Condition guides
Treatments & the science
- Stem Cell Therapy Overview
- Introduction to Stem Cell Therapy
- Umbilical Cord Stem Cells (UC-MSCs)
- Mesenchymal Stem Cell (MSC) Therapy
- How Stem Cells Work
- Safety & Treatment Process
- Exosome Therapy Overview
- How Exosomes Work
- Stem Cells vs Exosomes
- Intravenous (IV) Stem Cell Therapy
- Intrathecal Stem Cell Therapy
- Longevity Program
- See all treatments →
International patient support
Ask our medical team about treatment for Chronic Kidney Disease (CKD).
Send your diagnosis, recent reports, imaging and current medication. Our medical team reviews them and explains which regenerative medicine options may fit your case, and what treatment in Istanbul would involve.
Nothing needs to be booked to begin. Our patient coordination team plans your visit to Istanbul once your treatment plan is agreed.



