Avascular Necrosis (AVN) Stem Cell Therapy in Istanbul

Every part is itemized rather than bundled: the imaging review, whether one joint or two are covered, the route of administration, fluoroscopic guidance, sedation, theatre time where core decompression is part of the plan, and the imaging arranged at review. Our patient coordination team sends that breakdown in writing, with the clinical reason beside each line, before you commit to travel.

Rebuilding a segment of bone that has already collapsed is not what this research describes, and our medical team will not suggest otherwise. Once the subchondral bone has lost its shape, the joint surface above it is mechanically different and that is an orthopedic problem rather than a signalling one. Work in avascular necrosis centres on the pre-collapse setting, where there is still viable bone around the lesion to work with, and the goals we write down are about weight-bearing pain, walking distance and sleep.

It changes the whole conversation. Early disease, where the bone under the cartilage is still intact, is the setting this work is built around and where our medical team will look hardest at a plan. Once the dome has begun to flatten or collapse, the honest route is an orthopedic opinion about grafting or replacement. Our team reads the MRI itself rather than working from the stage alone, because lesion size and how much of the weight-bearing dome is involved matter just as much as the number on the report.

Your plan states it before you book flights: the assessment day, the procedure itself, the observation period afterwards, the weight-bearing restrictions for the days that follow and the point at which our team is comfortable with you flying. A procedure that places material into bone carries more restriction than a simple joint injection, so the stay is planned around that rather than around a return ticket booked in advance.

Yes. Our regenerative medicine program works with mesenchymal stromal cells (MSCs) grown from Wharton's jelly, the gelatinous tissue inside the umbilical cord. It is donated after a healthy birth with written maternal consent, from tissue that would otherwise be discarded, so nothing is taken from mother or baby and none of the ethical questions attached to embryonic sources arise. Because these cells expand readily in culture, a batch is characterised and release-tested before it reaches anyone. Your written plan names the material, how it is prepared, the dose, the route of administration and the schedule, and our medical team explains why each of those was chosen for your case.

Wharton's jelly is a young, perinatal tissue rather than an adult one, so the starting material does not carry the age or the health history of the person being treated, and nothing has to be harvested from you on the day. These cells also have a low-immunogenicity profile, which is why this source is studied for use between unrelated people. Most of all, they are strong secretors: the signalling molecules MSCs release are the mechanism most current research centres on, and that is what a plan is built around.

The length of stay follows your plan: the route of administration, the number of sessions, the monitoring after each one, and any mobility or assistance you need. Our patient coordination team confirms appointment dates, daily timings and the expected length of the visit in writing before you book flights.

No medical procedure is free of risk. Our medical team screens for infection, bleeding risk, medication interactions and other contraindications before treatment, explains the risks specific to the route used in your plan, and monitors you during administration and afterwards. If something makes treatment unsafe for you, we say so instead of proceeding.

Goals are set with you and described as aims, not results. Regenerative medicine treatments are planned individually, responses vary between patients and no clinical outcome can be guaranteed. Your plan states what will be measured, when it will be reviewed, and how treatment sits alongside the care you already receive.

Send your confirmed diagnosis, recent reports and imaging, your current medication list, previous procedures and the goals that matter to you. Our medical team reviews them remotely and comes back with an assessment of whether treatment in Istanbul is appropriate for your case, and what the next step would be.